Vaccines Found to Cause Diabetes in Children

August 19, 2008 by Not Autism  
Filed under Autism News, General

by David Gutierrez

Two new studies showing that vaccines increase the risk of diabetes have been published in the Open Pediatric Medicine Journal.

In a prior study, published in the journal Autoimmunity, Dr. J. Bartholomew Classen of Classen Immunotherapies and David Carey Classen of the University of Utah compared more than 100,000 children who had received between one and four doses of the hemophilus vaccine with more than 100,000 unvaccinated children. The Classens found that after seven years, children in the vaccination group had a 26 percent higher risk of developing diabetes than children in the non-vaccine group. This amounted to an extra 54 cases of diabetes per 100,000 children vaccinated.

The Classens noted that the vaccine itself is only projected to prevent seven deaths and seven to 26 cases of permanent disability per 100,000 children.

“Our results conclusively prove there is a causal relationship between immunization schedules and diabetes,” J. Bartholomew Classen said at the time.

In the more recent study, Classen examined data on the same vaccine, this time looking only at children who had a sibling with Type 2 diabetes. He found that the hemophilus vaccine led to an extra case of diabetes in one of every 50 such children, or 2 percent. This is 40 times higher than the already-elevated rate found in the Autoimmunity study.

“The recent data shows that common childhood vaccines are especially dangerous to children with a strong family history of diabetes,” Classen said. “Parents of a child with a strong family history of insulin-dependent diabetes … should know that the administration of a full series of vaccines may have a greater than 5 percent chance of causing their child to develop diabetes.”

Another study, published in the same issue of the Open Pediatric Medicine Journal, demonstrated a connection between the hepatitis B vaccine and Type 2 diabetes.

Autism Causes: Vaccines with Mercury / Thimerosal Linked To Autism

August 18, 2008 by Not Autism  
Filed under Autism News, General

Finally, what parents of children within the autism spectrum long have known is being validated  by the medical establishment in the United States - mercury in immunizations causes/triggers autism.  Mark Geier fought for years to have the CDC data release what was supposedly public epidemiological data concerning the skyrocketing rates of autism in the United States.  His analysis of the data was published in the March 10, 2006, issue of American Physicians and Surgeons.  This analysis shows that since mercury was removed from childhood vaccines, the alarming increase in reported rates of autism and other neurological disorders (NDs) in children not only stopped, but actually dropped sharply – by as much as 35 percent.

Using the government’s own databases, independent researchers analyzed reports of childhood neurological disorders, including autism, before and after removal of mercury-based preservatives. Authors David A. Geier, B.A. and Mark R. Geier, M.D., Ph.D. analyzed data from the CDC’s Vaccine Adverse Event Reporting System (VAERS) and the California Department of Developmental Services (CDDS) in “Early Downward Trends in Neurodevelopmental Disorders Following Removal of Thimerosal-Containing Vaccines.”

The numbers from California show that reported autism rates hit a high of 800 in May 2003. If that trend had continued, the reports would have skyrocketed to more than 1000 by the beginning of 2006. But in fact, the Geiers report that the number actually went down to only 620, a real decrease of 22 percent, and a decrease from the projections of 35 percent.

This analysis directly contradicts 2004 recommendations of the Institute of Medicine which examined vaccine safety data from the National Immunization Program (NIP) of the CDC. While not willing to either rule out or to corroborate a relationship between mercury and autism, the IOM soft-pedaled its findings, and decided no more studies were needed. The authors write: “The IOM stated that the evidence favored rejection of a causal relationship between thimerosal and autism, that such a relationship was not biologically plausible, and that no further studies should be conducted to evaluate it.”

As more and more vaccines were added to the mandatory schedule of vaccines for children, the dose of the mercury-based preservative thimerosal rose, so that the cumulative dose injected into babies exceeded the toxic threshold set by many government agencies. Mercury is known to damage nerve cells in very low concentrations.

The concern about vaccines may actually be underrated, as it is generally acknowledged that the voluntary reporting of such disorders has resulted in vast underreporting of new cases. For example, the Iowa state legislature banned thimerosal from all vaccines administered there after it documented a 700-fold increase in that state alone. California followed suit, and 32 states are considering doing so.

Up until about 1989, preschool children received only 3 vaccines (polio, DPT, MMR). Then during George Bush Senior’s presidency, the number of immunizations given to young children skyrocketed, fueled by the federal vaccine advisory board that was populated primarily by lobbyists for the vaccine manufacturers.  One of the vaccines added during this period was the mercury-laden Hepatitis B vaccine which was to be given within 24 hours of birth.  Heptatis B is primarily a STD (sexually transmitted disease).  The government could have instead instituted a blood test for pregnant women determine if their newborns were at risk rather than injecting all newborns with yet another vaccine.   By 1999, the CDC recommended a total of 22 vaccines to be given before children reach the 1st grade. Many of these vaccines contained mercury. In the 1990s approximately 40 million children were injected with mercury-containing vaccines.

The cumulative amount of mercury being given to children in this number of vaccines would be an amount 187 times the EPA daily exposure limit.

Between 1989 and 2003, there was an explosion of autism. The incidence of autism (and other related disorders) went from about 1 in 2,500 children to 1 in every 166. Currently there are more than a half million children in the U.S. that have autism. This disorder has devastated families leading to high divorce rates, shortened lives of parents (parents of special needs children live an average of 10 years less than other parents), and reduced standard of living to pay for expensive treatments.  

The response of the current Bush administration to this epidemic has been to deny there is an epidemic and try to hide the data from public scrutiny, while at the same time secretly putting in an addendum in to the Homeland Security Act specifically to prevent parents from suing vaccines companies for vaccine damage.  Over two years later, no one in the Bush Administration has yet come forth to take responsibility for authoring this addendum which has taken away the civil liberties of families of children with autism to seek compensation for the harm done to their children.  

The Bush administration also lobbied on behalf of special interests to defeat legislation that would have required mercury to be removed from the air-borne emissions of coal-firing power plants. About 48 tons of mercury are released into the air annually in the United States from hundreds of coal-burning plants.  A study in the journal “Health and Place” found that autism, a developmental disorder marked by communication and social interaction problems, increased in Texas counties as mercury emissions rose, said Claudia Miller, a family and community medicine professor at the University of Texas Health Science Center in San Antonio.  In areas near the coal burning plants, the rate of autism was 6 times higher than the national average.

In 1999, on the recommendation of the American Academy of Pediatrics and U.S. Public Health Service, thimerosal was removed from most childhood vaccines as a “precautionary” measure - i.e. without admitting to any causal link between thimerosal and autism.

The Geiers conclude that mercury continues to be a concern, as it is still added to some of the most commonly-used vaccines, such as those for flu:

“Despite its removal from many childhood vaccines, thimerosal is still routinely added to some formulations of influenza vaccine administered to U.S. infants, as well as to several other vaccines (e.g. tetanus-diphtheria and monovalent tetanus) administered to older children and adults. In 2004, the Institute of Medicine (IOM) of the U.S. National Academy of Sciences (NAS) retreated from the stated 1999 goal of the AAP and the PHS to remove thimerosal from U.S. vaccines as soon as possible…As a result, assessing the safety of TCVs [thimerosal-containing vaccines] is a matter of significant importance.”

The FDA allows vaccines to be labeled “mercury-free” even though they can still legally contain a certain amount of mercury, as mercury is actually part of the antiquated process of manufacturing vaccines, which has pretty much remain unchanged over 60 years.  

Also, worth noting is that these vaccines have a long shelf-life and the FDA did not issue a recall of the older vaccines containing higher levels of mercury.  This means that after 1999 children were still being immunized with unsafe levels of mercury.  Although it is less and less likely that children continue to be exposed to these older vaccines, it would be wise to check with the physician to ensure that the vaccines being administered were made after high levels of mercury were removed.  Also, flu vaccines without mercury may be requested.  Vaccines still containing mercury even if they have been labeled “mercury free”, may include DPT, Hepatits B, and HIB.

The main reason the flu vaccine is still being made with mercury is because the manufacturing plants have not been updated and it costs twice as much to make it mercury free, negatively impacting profits. 

Autism Research: Mirror Neuron Theory Update

August 18, 2008 by Not Autism  
Filed under Autism News, General

The latest research on mirror neurons, published in the November 7, 2007 issue of the Society for Neuroscience, may lead to new treatments for autism.  Mirror neurons are used to imitate others and acquire language.  When you perform a voluntary action, such as picking up a pencil, a set of “command” neurons activate.  When you watch someone else pick up a pencil a subset of these neurons, called ” mirror” neurons activate.  It is believed that mirror neurons enable us to learn through imitation.  In autism, however, the mirror neurons do not typically activate, when observing activity, leading to the implication that people with autism primarily learn by doing and do not tend to learn by watching others.  The latest research includes retraining the brain to activate the mirror neurons. In recent research on mirror neurons in monkeys by Peter Their, PhD at Tübingen University and Giacomo Rizzolatti, MD, at the University of Parma, a subset of mirror neurons were active only when the monkey was watching activity within reach; others responded only to actions performed in a place outside the monkey’s reach. Half of the mirror neurons showed activity that did not depend on how close the activity was to the monkey.  Thier believes that the closeness of the activity helps us monitor what goes on around us, and helps us determine the intentions of others and provides with the feedback we need to appropriately to interact with others. Other findings show that mirror neuron activity interprets facial expressions and actions of others.

The studies examined changes in brain wave patterns known as mu rhythms.  The sensorimotor cortex , the part of the brain that transmits signals for movement and sensing stimuli, suppresses mu rhythms when mirror neurons are activated.  However, this does not happen in children with autism.   Instead, the mu rhythms are actually enhanced.

Jaime Pineda, PhD, at the University of California , San Diego , first tested 23 neurotypical adults, who were asked to look at photos showing just the eye region of people making various facial expressions. In three separate trials, the subjects were asked to identify either the emotion, race, or gender of the people in the photographs. In a subsequent task, subjects looked at three-panel cartoon strips and were asked to choose a fourth panel that completed the strip-either the conclusion of a series of physical actions or the result of a person interacting with an object. A sequence of a prisoner removing the window of his cell, then looking at his bed, for example, could be followed by a frame of the prisoner asleep, yawning, or using the bedsheet to make a rope. Answering correctly depended on interpreting the cartoon character’s intentions appropriately or understanding how physical objects interact.

Pineda repeated the studies with 28 children, 7 to 17 years old, half of whom had autism. The other half were typically developing children.  In the children with autism, the mu rhythms were enhanced rather than suppressed during both tasks. This may mean that the mirror neuron system is disengaged. However, because the children still were able to perform the task, Pineda proposes that autistic children have found another coping strategy for understanding others that inhibits mirror neuron functioning.

This has lead Pineda to use neurofeedback training to successfully renormalize mu suppression in autistic children.  “Our findings are consistent with the idea that mirror neurons are not absent in autism,” Pineda says, “but rather are abnormally responsive to stimuli and abnormally integrated into wider social-cognitive brain circuits. This idea implies that a retraining of mirror neurons to respond appropriately to stimuli and integrate normally into wider circuits may reduce the social symptoms of autism.”

Other recent research by  Lindsay Oberman, PhD, at the University of California, San Diego, based on EEG recordings provide the first evidence of normal mirror activity in children with autism: People familiar to children with autism may activate mirror neuron areas of the brain in normal patterns when unfamiliar people do not.

Six videos were shown to a group of 26 boys, 8 to 12 years old; half had autism. Three videos showed images representing varying degrees of social interaction: two bouncing balls (the baseline measurement), three people tossing a ball to themselves, and three people throwing the ball to each other and off the screen to the viewer. The other set of videos showed people with varying degrees of familiarity to the subjects: strangers opening and closing their hand, family members making the same hand movement, and the subjects themselves doing the same.

EEG recordings from 13 electrodes in a cap showed that mu activity was suppressed most when subjects watched videos of themselves, indicating the greatest mirror neuron activity. For both groups, the measurements showed a slightly lower level of suppression when subjects watched familiar people in the video and the least when watching strangers. This indicates that normal mirror neuron activity was evoked when children with autism watched family members, but not strangers.

“Thus, to say that the mirror neuron system is nonfunctional may only be partially correct,” says Oberman. “Perhaps individuals with autism have fewer mirror neurons and/or less functional mirror neurons that require a greater degree of activation than a typical child’s system in order to respond.”

This normal mirror neuron activity in autistic children indicates that mirror system dysfunction reflects an impairment in identifying with and assigning personal significance to unfamiliar people and things, Oberman suggests.

Although this research may eventually lead to neurofeedback treatments to help autistic children learn through imitation, it also provides us with useful insights we can use to help our kids right now.  Obviously, these kids learn by doing and needed to be guided, hand-over-hand to acquire new skills.  One of the reasons ABA (Applied Behavioral Analysis) is so effective is because it uses this approach.  Other implications are that a child may not learn in a traditional classroom with a teacher lecturing at the front of a room, hands-on learning is best, that physical closeness to modeled activities is more stimulating than sitting far away and its best to have someone the child knows well and likes model activities for optimal learning through imitation.  This is incredibly useful information to have in our arsenal of techniques to help our kids.

Autism Recovery Story: Evan

August 17, 2008 by Not Autism  
Filed under About Autism, General

Recovery_storiesPresented By Generation Rescue

My son was diagnosed with ASD in July 2006 at the age of 4. He had always been called “quirky” by his pre-school teachers, but I knew in my heart that there was much more to his tantrums, speech delay, behaviors and massive gut issues than was being addressed.

So, the official diagnosis came of no real surprise. However, hearing the word “autism” sent a jolt through my soul that empowered me to get busy doing everything and anything I could to help my sweet, darling boy.

Immediately, we began with the traditional modalities: ABA, speech and occupational therapy. Slowly, I began to engulf myself in research. Thank Heaven for the internet! I enrolled him in a social skills group at the local University, a swim therapy group with his ST and OT; I started my own social skills program for other families with ASD children; but he was still struggling for control of himself.

So, I began reading about the integrative approach and the DAN! protocol. I just knew that this was our answer. I found an integrative pediatrician to supervise my GF/CF diet. We immediately began a mutli-vitamin, probiotic, L-Carnosine and DHA. Within three months, it was like I had a totally different child. He could have a conversation! He began to engage others in play rather than just parallel play. He was not fixated on certain toys. (His happened to be Thomas the Train). He became potty trained and was having more normal BM’s.

The true testament to my son’s recovery was my husband’s return from a four month military deployment. I began the diet and intervention when my husband left. When we picked my husband up at the airport, he tearfully shared, “I finally have my little boy”. It was the most dramatic thing he’d ever seen.

Prior to his witnessing it, he didn’t really believe that it would work, but he stands by the diet and supplements as the tools that turned our son around.

My son no longer meets the diagnostic criteria for autism; and we are ecstatic to share our story through our support group (and everywhere else) of our success. I diligently seek to help others initiate their GF/CF programs, eliminate toxins from their diet, as this is a massive undertaking; but it is SO worth the effort.

And so to my beautiful and special son, Evan, I say—shine on my love, shine on!

Kelli
Mother of Evan, age 6
Previously diagnosed with Autism

Autism Discussion with Dr. Goldberg - October 2007

August 16, 2008 by Not Autism  
Filed under Autism News, General

Below is a pared down/generic version of the 2 Oct 2007 NIDS Chat, organized by topic.  I wasn’t able to copy some key answers regarding the drug trials, so I’ve used brackets to synopsize some missing questions and answers.

DRUG TRIALS:

Dr. G - Future treatments are evolving, looking IF anything more promising…BUT need to finalize “i’s” and “t’s” [on drug trials] and start moving (hopefully ready to go).

Dr. G -  Bright note…more of the discussions [for trials] are going for “sooner than later” time frame…kids will hopefully be expedited (THAT’S VERY good news…as long as it happens :) )

Parent – Do you have more of an idea of who will be participating in your research.  Will it be new patients only?

Dr. G – No – goal will be controlled trials, and application (??
fairly quickly) with population I am working with (efforts being discussed now how we could cut corners, save time, BUT it all has to
finalize)

Parent – So for us oldies, are we looking at 6 mos or 2 yrs?
[transcript response is missing, but answer was essentially that the window was anywhere from 1-3 years, depending upon how quickly things moved]

Parent – May I ask, do you already have an immune modulator formulated?  [transcript response is missing, but there is an identified drug for the trials]

Dr. G – The bigger battle for all of you (the med WILL happen), is while everyone is saying “neuro-immune / viral” they are NOT throwing the switch, recognition that so much of this is really medical, really not psychological…it is inappropriate [portion possibly missing]

Parent - Any comments regarding attempt to get autism classified as an orphan disease?

Dr. G - Attempts at “orphan drug” or not WILL be influenced to some degree by how much awareness (and pressure) we put on the FDA and society to speed up correct answers…THAT may have a big effect on time, availability [of drug for trials]…that’s why I keep saying, NOW is the time to focus and break through as a major effort…it will speed things up, benefit all of you…IT is NO longer a matter of will [the] money [be] there – it is.  …BUT pressure.

—-

MEDICATION QUESTIONS (BIPOLAR, SSRIs, MAOIs, PSYCHOTIC MEDS):

Dr. G - Now 800,000 children are labeled, “Bi-Polar” (750,000 or more will be “neuro-immune / viral”) – another disaster

Dr. G - [As part of discussion with parent of a bi-polar child] There is no question at this point that a lot of “psychiatric” labels are going to be medical in origin BUT if we treat these kids (and
adults) “psychologically” over the next decade, it will be a part of enlarging disaster.

Dr. G – [first portion cut off] …the present situation is a complete disgrace (but since many are profiting, do not hear their voices fighting to change this)

Dr. G - [IRT parent comment about bi-polar child’s lethargy on multiple medications]  As I have written about, and express…children are supposed to be energetic, bright, alert.  ANY child no so, deserves a medical evaluation…there WILL BE reasons (medical NOT psychological)

Parent – What can I say to [my child’s] Dr to make [him] concerned enough to look at the cause [of my child’s excessive tiredness]?

Dr. G - …starting point…whether Autism, or bi-polar, or atypical ADHD, or…IT is physically impossible, scientifically impossible to have the numbers presenting without it being a disease process.  Come from that direction.  Obtain the DVD from my talk in Tupalo, MS (Sep
2005) – meant to give a way to help you or others build the right medical position and logic to make sense (in a regional center mixed audience…75-80% read)

Dr. G - IF [illness involves a] NIDS component, stimulant med WRONG idea…look towards an SSRI (but try to check out viral issues).

Parent – I know an SSRI is the first choice, but what if no response and a MAO-I (monoamine oxidase inhibitors, class of anti-depressants) is effective only …does it have some anti-inflammatory/benefits that SSRI would have – just more `dirty?’

Parent – What is [an] SSRI?

Parent – Selective Serotonin Reuptake Inhibitor, i.e., Prozac, Paxil, Celexa, Luvox, Lexapro, Zoloft.

Dr. G - …I try to base all my choices on what is logical, likely to help a brain / child become healthier…do not believe there is any long term benefit to MAO’s (do not use them with any of the children)

Dr. G – Generally not as comfortable with Lexapro in children (but may be OK) – DO not like Luvox (not a simple SSRI)

Parent – If there does seem to be a benefit of less crying, more calmness, less agitation, less depressed mood, do you think speaking in terms of Neuroimmune/health of brain [child in question is a teenager] - No MAOI is better than a MAOI?

Dr. G – Difficulty is MAO is not helping part of the brain mature, improve…something may be better than nothing, but goal of NIDS is to wind up with a healthier choice of meds (as needed).  OFTEN may have so many difficulties, weird symptoms, issues, that “heavy” meds may seem indicated…but as the medical and immune issues are cleared, do not have to go that way with any child I work with.

Dr. G – [IRT discussion of using psychotic and other drugs on children] …part of issue of “controlling” a child, instead of addressing or helping the medical issues.  Part of my major frustration, because your children are being mis-diagnosed, mis- treated by much of the medical system, and then you as parents (your
children) become vulnerable to an alternative medical system ALSO creating far more harm than good (but trying to tell so many of you it’s healthy, it’s natural…

—–

EPSTEIN-BARR VIRUS (EBV, a herpes virus):

Parent - Do we know the significance of EBV [titers]?

Dr. G - EBV may now be much more significant than we thought.  Can’t
say for sure yet, but rather than being a false elevation, the titer
may reflect some mutated virus mimicking EBV or…

Dr. G – [IRT parent question as to whether patient’s EBV titers
should be checked] …routinely, EBV, CMB titers should be checked
(along with HHV6, etc)

—-

DARK EYE CIRCLES:

Parent - What’s the next step in dealing with dark circles when anti-
virals aren’t taking care of them?

Dr. G - Depends on blood work.  Dark circles ARE viral or allergic in
origin.

—-

NIDS IN FAMILY?

Parent – my child has NIDS and now my 1-yr old nephew is in the
hospital; can’t keep any food down.  He’s severely underweight and
his siblings present with food allergies and ADD type behavior.
Could his reaction to food be NIDS too?

Dr. G -…absolute yes.  May just be extreme sensitivities, allergies
OR may be full-blown NIDS issues, but IF other answers have surfaced,
this is the direction they should be pursuing.

—-

RECENT BOOK ON AUTISM:

Parent – Do you think all the press that Jenny McCarthy is getting
will help your cause or is she going down a different path?

Dr. G – any focus on “neuro-immune, viral” is good – BUT as said
earlier, saying it, but without fully understanding what this means
for her child and others yet, is not achieving what you all need for
your children.

—-
LYME-AUTISM CONNECTION?

Parent – What are your thoughts on the Lyme-autism connection?

Dr. G – …NO better than the CFS/CFIDS Lyme connection…a RARE
possibility in some, but very unlikely in general.

—-

ISOPRINOSINE:

Parent – Are you looking at any new treatments that are already
available?

Dr. G – With the data we’ll be getting, other ideas may be possible
(targeted based on labs), but there is no agent currently available
that can do what must be done.

Parent – Dr. G, you had mentioned Isoprinosine before, I was
wondering if you came to a conclusion yet on your feelings about it?

Dr. G – Still checking, but may be worth discussing for a few kids
(will know more in next few weeks).

—-

TENEX:

Parent – I was also curious if you were to use Tenex on a confirmed
diagnosis of ADHD (NeuroSPECT scan) – do you have to first and ONLY
address viral issues/other medications for a 6 month-1 year (approx)
period before something like Tenex can be used to calm and focus the
patient?

Parent – What is Tenex?

Parent – Tenex is a blood pressure medication which has been FDA
approved for the use of ADHD – (look it up on Wikipedia.org)

Dr. G – Great question.  The key here is [to] “peel apart each layer” –
no you do not have to wait months before moving onto the next step,
but you must do one thing at a time to know what is working or  not.

Parent – Interesting – makes complete sense…been working with a
wonderful and high progressive doctor who is somewhat familiar with
the Neuroimmune type connection…so this is great information.

—-

IVIG/IMGG:

Parent – At what point do you start recommending IVIG [intravenous
immuno globulin] or IMIG [aka IMGG, intramuscular gamma globulin)]?

Dr. G – Depends on QIgG (total IgG) levels, overall immune system,
viral factors…very liberal (at this point) about trial of IMGG, still
very hesitant (rare exception) for IVIG…

Parent – Is that only warranted when there are “no” antibodies or it
is both no or super high?

Parent – Dr. G, I understand your concern over IVIG possibly passing
more diseases but I’m not sure how IMIG differs from IVIG other than
the fact that one is a shot and one is IV.  Wouldn’t IMIG be just as
risky?

Dr. G - For “specifics” – many variables.  Discuss at f/u…IMGG is
processed / made differently than IVIG, that’s why  it’s different.

—-

PROBIOTICS:

Parent – What if probiotics simply cause things to become worse –
OCD, agitation, mood fluctuation…even when using a basic Kyo-dophilus
or Acidophilus?  At the same time having to go on a antibiotic
treatment for a bacterial GI infection?  It kills off the flora – but
repeated tried with probiotics make things worse…what then?

Dr. G – Even though I am not opposed to a clean, plain probiotic at
times, the reactions you name show how any parent must look, evaluate
what they give a child, whether that product agrees with their child,
and whether impurities are causing problems.

Parent – alright, helpful insight.  I simply understand probiotics to
be used to help the gut flora and “help” prevent “Yeast/Candida” –
and the use of an antibiotic for a bacterial infection kills off part
of that flora to keep a Yeast infection down.  So it is better to
simply forego the probiotic and hope a fungal infection doesn’t
spring up?

—-

HERBS:

Parent – How do you feel about herbs?

Dr. G - Not very positive about most herbs or non-pharmaceutical
supplements.  What is being seriously missed out there, is ANY
product meant to be healthy, but which “pushes” or activates the
already overly sensitive, overly revved up immune system, is going to
do far more harm than good!!!

—-

GENERAL IMMUNE:

Dr. G -  [IRT parent general comment about immune issues]  Think
chronic immune / viral stress > breakdown > dysfunction > MS or
Lupus, rheumatoid syndrome, cancer, leukemia, lymphoma, etc (nice
little things…we must start thinking preventatively or we’re all in
for an enlarging, unaffordable health care crisis / social, medical,
disaster.

Dr. G – I’m seeing children present with an obvious viral
encephalitis, seizures, and NOT be worked up [because they’re
categorized] under the guise of the “A word”

Dr. G – With the talk of “neuro-immune” we need to recreate a correct
focus…or as ready to listen more, academics will continue to shut
down at the half truths, then “sci fi” being presented.

—-

Dr. G - Great set of questions and issues tonight…but share
frustration with all of you.  With a VERY bright upside coming,
hoping we can get together, focus, break through…

Autism Causes: The Seventies Most Vaccinated Child

August 16, 2008 by Not Autism  
Filed under Autism News, General

Military_bratBy J.B. Handley

I grew up a “Military Brat” and always figured I must have been one of the most vaccinated kids of the 1970s. Born in May of 1969, I lived in Singapore (where I was born), Laos, Mexico, and Korea before I was ten and also traveled to Thailand, Malaysia, Hong Kong, Japan, and the Philippines during this same time period.

If you took a travel itinerary like that to your pediatrician today, he’d back up the vaccine truck and start pumping you and your child full of every vaccine he had in inventory and probably special order some unique ones, too.

I often heard my own son’s pediatrician talk about “deadly foreign diseases” being “only a plane ride away” as he sought to allay our concerns over the volume of vaccines being given to our own kids in the late 1990s and early 2000s.

David Kirby’s Huffington Post article (HERE) about vaccines in the military and the incredibly high rate of adverse events spurred me to write about something I recently unearthed: my own shot records.

As a reminder, the CDC recommends that today’s children, by the age of 6, receive 36 vaccines. You can see a chart HERE that also compares today’s 36 to the 10 children received in the early 1980s.

But what about the 1970s? I’ve never been able to find a vaccine schedule before 1983, but you’d sure think my own experience would be at the extreme upper end of vaccines given to a child. Not only did I live in multiple foreign countries, but I was also part of the tight military healthcare system where mandatory doctor visits are part of any overseas travel protocol. They could never miss me!

So, here’s my schedule.

To keep it simple, I am only listing my vaccines from birth to age 6 so I can compare it to today’s schedule:

March 1970:   Oral Polio
July 1970:      Measles (Rubeola)
Sep. 1970:     DPT
April 1974:     Oral Polio
April 1974:     Typhoid

That’s it. I got 5 vaccines. Today’s kids get 36 in the same time period. And, these are typical American kids who may never leave this country. I had lived in or visited nine countries, a number of them third world!

Notable that my first vaccine was given when I was 10 months old. Once, I got 2 vaccines in the same visit.  Otherwise, they were a minimum of 4 months apart, and in some cases YEARS apart.

What can we learn from one kid’s vaccine schedule?

We can learn that the US Military is learning the same things we parents are: the insane US vaccine schedule is something very, very new.

We are witnessing a medical experiment being done on our kids and servicemen and women every day without precedent, without proper testing, and without acknowledgment for the extreme consequences of the insane number of vaccines we are giving our citizens.

This insanity is the product of a CDC that is corrupt and has let vaccine manufacturers make most of the rules. The question now is how this all will end. Who will step in and have the courage to reform a vaccine schedule that has clearly gotten out of control?

If a child of the 1970s can survive nine foreign countries with 5 vaccines, surely we can reduce the number of vaccines being given without putting our children and military at risk.

JB Handley is co-founder of Generation Rescue and Editor at Large for Age of Autism.

Is BBQ GFCF? Texas Study on Diet and Autism

August 14, 2008 by Not Autism  
Filed under Autism News, General

Gluten_free_tagBy Kim Stagliano

GFCF diet is getting attention and research at UT’s Health Science Center at Houston, Texas. I’m happy to see the study underway, since without proof on paper by scientists at a university, pediatricians will continue to turn around during the exam and roll their eyes when we mention the diet.  Just as they did to parents who swore by the Feingold Diet before a study illustrating the adverse effects of artificial colors and flavors on behaviors proved what Mom and Dad had known for years. To its credit, the AAP did put out a statement about the success of the Feinfold diet for some children. It’s a shame American kids aren’t put onto this diet as a matter of course and “prescription” from a doctor (the only way many parents will try the diet) before ADHD drugs.

I have a couple of questions about this GFCF diet study.

1) Who is funding this study? 2) Why only four weeks long? Many of us did not see changes within this short time period. 3) How do they plan to ensure that there is no “cheating?” Will they give the families all of their food for the four weeks? It’s very hard to ferret out all sources of gluten and casein when you’re new to the diet and even as a veteran. 4) Who is funding this study? (Yes, I realize that one repeats.)

(HealthNewsDigest.com)- HOUSTON — Researchers at The University of Texas Health Science Center at Houston have embarked on one of the first double-blind, clinical studies to determine whether gluten and dairy products play a role in autistic behavior as parents have anecdotally claimed.

The pilot study is one of seven current studies on autism in the Department of Pediatrics and the Department of Psychiatry and Behavioral Sciences at The University of Texas Medical School at Houston.

“There’s a lot of misinformation, so that’s why this study is so important,” said Fernando Navarro, M.D., assistant professor of pediatrics at the medical school and lead investigator of the study. “Hundreds and hundreds of parents think this works but we need serious evidence.”

Read the full article HERE.

Kim Stagliano is Managing Editor of Age of Autism. She just ate two pieces of birthday cake. One she baked for her husband’s birthday, loaded with gluten and casein. The other she baked for her children, GFCF. Which tasted better? Only her hairdresser knows… (and if you’re too young to get that line, my apologies. Google it.)

Autism Causes: Boost Vaccine Safety

August 13, 2008 by Not Autism  
Filed under Autism News, General


Published on: 08/12/08In recent months, a vitriolic public health debate has been taking place, sparked by the case of Hannah Poling, a 9-year-old Georgia girl with autism. Her parents, neurologist Jon Poling and his wife, Terry, filed in federal no-fault vaccine court, asserting that vaccines caused their daughter’s condition and asking for compensation for the lifelong care Hannah will require.

Without a formal hearing, the federal government conceded the nine vaccines Hannah received on July 19, 2000, significantly aggravated an underlying medical condition — mitochondrial dysfunction, or an impaired functioning of how cells create energy. This predisposed Hannah “to deficits in cellular energy metabolism and manifested as a regressive encephalopathy with features of autism spectrum disorder.” In simple terms, Hannah has autism.

This concession, which became public in March, has prompted strong reactions. Some government officials are, ironically, fueling public distrust of immunizations by failing to acknowledge — much less address — emerging vaccine safety issues. And every day, more parents and some pediatricians reject the vaccination schedule.

Former National Institutes of Health Director Bernadine Healy has entered the debate, saying the scientific community should never turn its back on a hypothesis out of fear for what it might reveal: If you know there is a susceptible group, she said in a television interview, “you can save those children. If you turn your back on the notion there is a susceptible group … what can I say?”

Yet, amazingly, just last month the Federal Interagency Autism Coordinating Committee refused to mention vaccine safety in its strategic plan.

The matter is urgent. One in every 150 children has an autism spectrum disorder. Mitochondrial dysfunction is not rare among these children. The best evidence suggests that at least 4 percent — and perhaps 20 percent or more — of autistic children have mitochondrial dysfunction.

With stakes this high, it’s time for policy-makers to take five common-sense steps to ensure that more children are not damaged by the very vaccines intended to protect them.

• With Marshall Plan dispatch, Congress should launch a bold, nothing-off-the-table program of basic scientific research on the role of mitochondrial dysfunction and neuro-inflammation in autism and other disorders. Funding — $200 million for starters — must not be taken from the Vaccine Injury Compensation Program.

• Reform vaccine practices so they are as safe as possible for both children in general and susceptible subgroups. Examine the schedule, number and frequency of vaccines, use of combination vaccines, preservatives used and ages at which vaccines are administered. Find ways to identify children for whom vaccination or another event might cause or worsen mitochondrial dysfunction, leading to autism. Study siblings to identify biological markers that could lead to prevention, screening and treatment.

• Piggyback new research onto existing efforts. Use the Newborn Screening Saves Lives Act to propel advances concerning genetic and metabolic disorders. Modify the National Children’s Study to test alternate vaccine schedules. And integrate new analyses into ongoing studies, such as mitochondrial research already under way at Johns Hopkins University and the Cleveland Clinic Foundation.

• Identify children nationwide who have abrupt developmental regressions, including those that are vaccine-related, and speed them into research and intense early intervention. And strengthen the Vaccine Adverse Event Reporting System, including imposing serious consequences for health care providers who do not report bad reactions.

• Improve the Vaccine Injury Compensation Program. Encourage parents to focus on early intervention by allowing longer than three years to file. Update the Vaccine Injury Table, making it easier for families to receive compensation as new discoveries emerge. And explore limiting compensation to the most critical immunizations, returning adverse reactions from other vaccines to the regular court system.

A loud wake-up call from a beautiful little redheaded girl from Georgia has provided policy-makers with a historic opportunity to tackle critical issues of vaccine safety. If they fail to answer, what can I say?

— Margaret Dunkle, Hannah Poling’s great-aunt, directs the Early Identification and Intervention Collaborative for Los Angeles County. She is a senior fellow at the Center for Health Services Research and Policy at George Washington University.

Mitochondrial Disease: 1 in 200 People Carry Mutation

August 12, 2008 by Not Autism  
Filed under Autism News, General

BOTH MITOCHONDRIAL “DISEASE” AND “DYSFUNCTION” APPEAR TO BE MORE COMMON THAN PREVIOUSLY THOUGHT — IMPLICATIONS FOR AUTISM, OTHER DISORDERS ARE “EARTH SHATTERING.”
In February, when the US government conceded that vaccines had caused an autism-inducing reaction in little Hannah Poling, most experts declared that her underlying condition, a mitochondrial disorder, was exceedingly rare - so rare, in fact, that it had no bearing on other autism cases.

But today, the United Mitochondrial Disease Foundation announced a “landmark research finding” showing that at least one in 200 healthy humans “harbors a pathogenic mitochondrial mutation that potentially causes disease.” The finding was published in the current issue of the American Journal of Human Genetics.

“This is earth shattering news,” UMDF Executive Director and CEO Charles A. Mohan, Jr. told me this evening. “Some of my colleagues are calling it ‘revolutionary.’ We have shown that mitochondrial disease is not rare.”

Mitochondria are the little powerhouses found within most cells, and which produce most of the body’s energy. Mitochondria are key for proper neurotransmission and, for obvious reasons, are highly concentrated in cells of the brain and central nervous system.

Up until now, estimates of mitochondrial disease rates have held steady at about 1-in-4000 people. But this study shows that 20 times that number have genetic mutations that could cause mitochondrial disease.

“What this says to me is that more than 1-in-4,000 people have mitochondrial disease,” Mohan said. “And it tells me that 1-in-200 could develop some type of mitochondria-related disease over the course of their lifetime, depending in part on environmental triggers.”

Mitochondrial disorders are found at “the core of many well known diseases and chronic illnesses, such as Alzheimer’s disease, Parkinson’s disease and autism spectrum disorders,” a statement from the UMDF said today.

Humans have two types of DNA: nuclear, and mitochondrial. The study looked at 10 mutations in mitochondrial DNA that are known to cause disease, and identified them in the cord blood of 1 in 200 newborn children.
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The study looked exclusively at classic mitochondrial “disease.” In the classic form, inherited mutations of mitochondrial DNA are passed down through the mother, causing a wide variety of pathologies, including seizures, digestive problems, paralysis, blindness, heart disease, neurodevelopmental disorders and other problems.

The classic form is often quite severe, and sometimes fatal. But it is not rare.

Which brings us to Hannah Poling: She does not have “classic,” maternally inherited mitochondrial disease.

Hannah does share the same single-point mutation in mitochondrial DNA as her mother, Terry. But this mutation is apparently benign (Terry Poling is just fine), is not described in the medical literature, and is not associated with any pathology at all.

Instead, Hannah seems to have had a much milder, even asymptomatic form of mitochondrial “dysfunction” - one that led to reduced cellular energy, but no obvious signs of severe mitochondrial “disease.”

In April, I reported that researchers in Baltimore were studying 30 children at one autism clinic who all had nearly identical markers for mild mitochondrial dysfunction. One of them was Hannah Poling.

All 30 children were developing normally until they encountered some type of immunological stress and began showing signs of regressive autism soon afterwards.

In 28 cases, the doctors said, typical childhood fevers caused the stress, while in the other two cases, including Hannah, vaccines appeared to be the exacerbating factor.

The doctors - who spoke on a CDC conference call that included executives from the health insurance industry — reported that mitochondrial dysfunction was found in autism “in numbers that make it not a rare occurrence.”

Some estimates currently put the rate of mitochondrial dysfunction in ASD at 7-20%, while rates among regressive autism cases could climb much higher than that.

This milder form of mitochondrial disorder, the doctors said, was probably caused by a mutation found in nuclear (as opposed to mitochondrial) DNA, and inherited through the father — rather than through the mother, as in classic mitochondrial disease.

Shockingly, the nuclear DNA mutations that bring risk of dysfunction could be as common as 1-in-400 to 1-in-50 people - though no one knows how many people have developed actual mitochondrial disorders because of it.

Even so, we can now assume that classic mitochondrial “disease” described in this study (via mutations in maternal mitochondrial DNA) and mild mitochondrial “dysfunction” found in Hannah and others (via mutations in paternal nuclear DNA) are both associated with increased risk for autism.

And we can also now assume that neither form of mitochondrial disorder is rare. Moreover, whether the low cellular energy originates in mitochonrial DNA or nuclear DNA mutations, either way it could confer increased risk for autism.

That would mean a significant number of children between the ages of 1 and 2 who are walking around right now, potentially vulnerable to autistic regression triggered by some acute immune stressor - whether vaccine related or not.

“Mitochondrial dysfunction represents a major unexplored area of human biology of vital importance to human health,” the UMDF statement said, noting that it also has been implicated in autoimmune diseases such as multiple sclerosis and lupus.

“While it cannot yet be said that mitochondrial dysfunction causes these problems, it is clear that mitochondria are involved because their function is measurably disturbed,” the statement said.

This new study suggests that, “mitochondrial dysfunction is a major underlying risk factor for human disease,” said Dr. Douglas C. Wallace, professor of molecular medicine and director of the Center for Molecular and Mitochondrial Medicine and Genetics at the University of California-Irvine.

He should know. Dr. Wallace is one of the world’s leading mitochondria researchers, and a member of the UMDF’s Scientific and Medical Advisory Board. He also has a 23-year-old son with autism.

In April, Dr. Wallace told the Vaccine Safety Working Group of HHS’s National Vaccine Advisory Committee that over-vaccination of people with mitochondrial disorders was a deep concern, especially in light of Hannah Poling, who got nine vaccines in one well-baby visit.

“We have always advocated spreading the immunizations out as much as possible because every time you vaccinate, you are creating a challenge for the system,” Dr. Wallace testified. “And if a child has an impaired system that could in fact trigger further clinical problems.”

I take that to mean that children with impaired mitochondria might also have impaired immune systems. And children with impaired immune systems might not be able to handle, say, nine vaccines given at once.

The CDC says that multiple simultaneous vaccines are safe, “for children with normal immune systems,” but makes no mention of the risk for everyone else.

But, as Dr. Wallace put it, “We do not know what is safe. We do not know what is not safe. We do not know the actual risk of a person with light mitochondrial disease has and being challenged either by vaccination or by a severe infection.”

“Is there a relationship between mitochondrial disease and vaccination and mitochondrial disease and autism?” Dr. Wallace asked rhetorically. “Would a vaccination or infection initiate an incipient mitochondrial disease, as has been suggested?”

Only major investments in scientific research will answer these questions, which have become particularly pressing now that we know that mitochondrial disorders are anything but “rare.”

“This will help us educate key members of Congress to motivate and encourage NIH to appropriate more funds to focus specifically on mitochondrial dysfunction and disease,” Mohan told me. “We would like to see this result in a better understanding of the links between energy metabolism and what we call the “sexy diseases.”

I likewise hope our nation’s researchers will jump on this particular scientific train before it leaves the station.

It would appear that far more lives are at risk for far more diseases (well beyond autism) than we ever imagined.

Diet And Autism Research Focuses On Which Foods May Affect Autistic Behavior

August 11, 2008 by Not Autism  
Filed under Autism News, General

Researchers at The University of Texas Health Science Center at Houston have embarked on one of the first double-blind, clinical studies to determine whether gluten and dairy products play a role in autistic behavior as parents have anecdotally claimed.The pilot study is one of seven current studies on autism in the Department of Pediatrics and the Department of Psychiatry and Behavioral Sciences at The University of Texas Medical School at Houston.

“There’s a lot of misinformation, so that’s why this study is so important,” said Fernando Navarro, M.D., assistant professor of pediatrics at the medical school and lead investigator of the study. “Hundreds and hundreds of parents think this works but we need serious evidence.”

Autism is a complex neurobehavioral disorder linked to early abnormalities of brain development. According to the National Institute of Neurological Disorders and Stroke, it affects up to six of every 1,000 children and is characterized by impaired social interaction, problems with verbal and nonverbal communication and unusual, repetitive or severely limited activities and interests.

Researchers have discovered that there are differences in the central nervous system’s anatomy and function in those diagnosed with autism, but the cause of the disorder is unknown. Experts theorize it may be a combination of genetics and environment.

“A lot of children with autism have gastrointestinal problems such as constipation and diarrhea. Whether these problems are related to brain development is open to question,” said Katherine Loveland, Ph.D., co-investigator and professor of psychiatry and behavioral sciences, pediatrics and biomedical sciences at the health science center. “There are neurotransmitters and neuroreceptors in the gut that correspond with those in the brain. There are some scientific reasons to think that some kids may benefit from this diet.”

For the double-blind study, funded in its initial phase by supplemental funds granted by the Department of Pediatrics, researchers will enroll 38 autistic children ages 3 to 9. They will look at the influence of gluten and milk proteins in the intestinal function. Gluten is a protein in wheat; casein and whey are proteins in milk. Casomorphin, a peptide in milk; and gliadomorphin, a peptide in gluten, are thought to be related to changes in behavior in these children. Children will be taken off gluten and dairy products before the four-week study and then half will be given gluten/milk powder and half will be given a placebo powder.

Researchers will study intestinal permeability (leaky gut) through urine collection and behavior through psychometric testing.

Co-investigators for the study are J. Marc Rhoads, M.D., professor and director of gastroenterology at the medical school, and Deborah A. Pearson, Ph.D., professor of psychiatry and behavioral sciences.

Children will be enrolled through the UT Physicians pediatric gastroenterology clinic and The University of Texas Mental Sciences Institute. Navarro and Rhoads are attending physicians at Memorial Hermann hospitals. For more information on the study, call 713-500-5669.

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The information on this website is for educational purposes only. It is given in good faith to help people understand more about what our children are dealing with. It is not intended to replace or supersede patient care by a health care provider. If an individual suspects the presence of an illness, that individual should consult a health care provider who is familiar with the diagnosis and treatment of their condition.